PRF1 protein (Oryctolagus cuniculus) - STRING interaction network

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Predicted Interactions

gene neighborhood

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gene co-occurrence

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textmining

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protein homology

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[Homology]

Score

PRF1

Perforin 1. (583 aa)

Predicted Functional Partners:

LOC100346285

0.920

LOC100346200

0.919

G1TX71_RABIT

0.894

FASLG

0.853

CD8A

0.841

NKG7

0.798

KLRD1

0.774

LOC103351183

0.766

IFNG

0.755

GZMH

0.754

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD8A	FASLG	ENSOCUP00000045245	ENSOCUP00000022211	Ig-like domain-containing protein.	Fas ligand; Belongs to the tumor necrosis factor family.	0.575
CD8A	G1TX71_RABIT	ENSOCUP00000045245	ENSOCUP00000021671	Ig-like domain-containing protein.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.597
CD8A	GZMH	ENSOCUP00000045245	ENSOCUP00000011332	Ig-like domain-containing protein.	Granzyme H; Belongs to the peptidase S1 family.	0.577
CD8A	IFNG	ENSOCUP00000045245	ENSOCUP00000039594	Ig-like domain-containing protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	0.880
CD8A	KLRD1	ENSOCUP00000045245	ENSOCUP00000026712	Ig-like domain-containing protein.	Killer cell lectin like receptor D1.	0.695
CD8A	LOC100346200	ENSOCUP00000045245	ENSOCUP00000015889	Ig-like domain-containing protein.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.633
CD8A	LOC100346285	ENSOCUP00000045245	ENSOCUP00000013087	Ig-like domain-containing protein.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.633
CD8A	LOC103351183	ENSOCUP00000045245	ENSOCUP00000011323	Ig-like domain-containing protein.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.477
CD8A	NKG7	ENSOCUP00000045245	ENSOCUP00000029324	Ig-like domain-containing protein.	Natural killer cell granule protein 7.	0.695
CD8A	PRF1	ENSOCUP00000045245	ENSOCUP00000006013	Ig-like domain-containing protein.	Perforin 1.	0.841
FASLG	CD8A	ENSOCUP00000022211	ENSOCUP00000045245	Fas ligand; Belongs to the tumor necrosis factor family.	Ig-like domain-containing protein.	0.575
FASLG	G1TX71_RABIT	ENSOCUP00000022211	ENSOCUP00000021671	Fas ligand; Belongs to the tumor necrosis factor family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.597
FASLG	GZMH	ENSOCUP00000022211	ENSOCUP00000011332	Fas ligand; Belongs to the tumor necrosis factor family.	Granzyme H; Belongs to the peptidase S1 family.	0.555
FASLG	IFNG	ENSOCUP00000022211	ENSOCUP00000039594	Fas ligand; Belongs to the tumor necrosis factor family.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	0.801
FASLG	KLRD1	ENSOCUP00000022211	ENSOCUP00000026712	Fas ligand; Belongs to the tumor necrosis factor family.	Killer cell lectin like receptor D1.	0.558
FASLG	LOC100346200	ENSOCUP00000022211	ENSOCUP00000015889	Fas ligand; Belongs to the tumor necrosis factor family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.617
FASLG	LOC100346285	ENSOCUP00000022211	ENSOCUP00000013087	Fas ligand; Belongs to the tumor necrosis factor family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.617
FASLG	LOC103351183	ENSOCUP00000022211	ENSOCUP00000011323	Fas ligand; Belongs to the tumor necrosis factor family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.730
FASLG	PRF1	ENSOCUP00000022211	ENSOCUP00000006013	Fas ligand; Belongs to the tumor necrosis factor family.	Perforin 1.	0.853
G1TX71_RABIT	CD8A	ENSOCUP00000021671	ENSOCUP00000045245	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Ig-like domain-containing protein.	0.597