STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCNDecorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (360 aa)    
Predicted Functional Partners:
EGFR
Receptor protein-tyrosine kinase.
    
 0.988
LOC103345451
TGFb_propeptide domain-containing protein.
    
 0.984
ENSOCUP00000037329
TGFb_propeptide domain-containing protein.
    
 0.984
ENSOCUP00000044284
TGFb_propeptide domain-containing protein.
    
 0.984
TLR4
TIR domain-containing protein; Belongs to the Toll-like receptor family.
    
0.976
G1TC56_RABIT
TGFb_propeptide domain-containing protein.
   
 0.975
IGF1
Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]
   
 0.973
TGFB2
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.963
ENSOCUP00000040886
Uncharacterized protein.
   
 
 0.957
TGFB3
Transforming growth factor beta 3.
   
 0.952
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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