STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRHPRGlyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (453 aa)    
Predicted Functional Partners:
AGXT
Serine--pyruvate aminotransferase.
  
 
 0.997
GLYCTK
Glycerate kinase.
 
 
 0.971
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family.
  
 0.957
HAO1
Hydroxyacid oxidase 1.
  
 
 0.944
GLO1
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 0.921
PSAT1
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
     
 0.892
AGXT2
Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.885
GLDC
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
   
 
 0.880
SDS
Serine dehydratase.
  
 
 0.846
AOC2
Amine oxidase.
     
 0.821
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.