Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UTS2BUrotensin 2B. (119 aa)    
Predicted Functional Partners:
G1T4V1_RABIT
Uncharacterized protein.
     
 0.922
CCKAR
Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
     
 0.746
CYSLTR1
Cysteinyl leukotriene receptor 1.
     
 0.668
CCK
Gastrin domain-containing protein.
     
 0.604
LOC100345534
Gastrin domain-containing protein.
     
 0.580
GPR65
G protein-coupled receptor 65; Belongs to the G-protein coupled receptor 1 family.
     
 0.572
PTH2
Parathyroid hormone 2.
      
 0.563
NPSR1
G_PROTEIN_RECEP_F1_2 domain-containing protein.
     
 0.549
LAMP5
Lysosomal associated membrane protein family member 5.
      
 0.544
EDNRA
Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.
     
 0.542
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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