STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCXDoublecortin. (361 aa)    
Predicted Functional Partners:
NES
Nestin; Belongs to the intermediate filament family.
      
 0.911
CAMK1D
Calcium/calmodulin dependent protein kinase ID.
 
 
 
 0.911
PSKH2
Protein serine kinase H2; Belongs to the protein kinase superfamily.
 
  
 
 0.907
CAMK1
Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily.
 
  
 
 0.905
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
 
 0.905
PNCK
Pregnancy up-regulated nonubiquitous CaM kinase.
 
  
 
 0.890
PSKH1
Protein serine kinase H1; Belongs to the protein kinase superfamily.
 
 
 
 0.870
BDNF
Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
      
 0.859
MAPKAPK3
MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.
 
      0.857
PHKG1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
 
      0.852
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.