STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)    
Predicted Functional Partners:
PCF11
PCF11 cleavage and polyadenylation factor subunit.
    
 0.999
CSTF3
Cleavage stimulation factor subunit 3.
   
 0.954
GTF3C3
General transcription factor IIIC subunit 3.
    
 
 0.954
FIP1L1
Fip1 domain-containing protein.
    
 0.953
CPSF2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.940
CPSF3
Cleavage and polyadenylation specific factor 3.
   
 0.923
CSTF2
Cleavage stimulation factor subunit 2.
   
 0.910
CPSF4
Cleavage and polyadenylation specific factor 4.
    
 0.908
TSEN2
tRNA splicing endonuclease subunit 2.
   
 0.887
LOC100344475
RRM domain-containing protein.
   
 0.866
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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