STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PENKUncharacterized protein. (430 aa)    
Predicted Functional Partners:
OPRM1
Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.993
OPRD1
Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.925
SST
Somatostatin.
  
  
 0.823
OPRK1
Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.715
PNOC
Prepronociceptin.
     
0.689
NPY
Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
     
 0.671
TAC1
C-terminal-flanking peptide; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles; Belongs to the tachykinin family.
   
  
 0.667
POMC
NPP domain-containing protein.
     
 0.642
TRPC5
Short transient receptor potential channel 5; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G- protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion.
      
 0.618
KLHL35
Kelch like family member 35.
      
 0.614
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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