| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APAF1 | CASP3 | ENSOCUP00000010200 | ENSOCUP00000036614 | Apoptotic peptidase activating factor 1. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | 0.998 |
| APAF1 | CASP8 | ENSOCUP00000010200 | ENSOCUP00000049942 | Apoptotic peptidase activating factor 1. | DED domain-containing protein. | 0.977 |
| APAF1 | CFLAR | ENSOCUP00000010200 | ENSOCUP00000009525 | Apoptotic peptidase activating factor 1. | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | 0.849 |
| APAF1 | FASLG | ENSOCUP00000010200 | ENSOCUP00000022211 | Apoptotic peptidase activating factor 1. | Fas ligand; Belongs to the tumor necrosis factor family. | 0.739 |
| APAF1 | G1SSE7_RABIT | ENSOCUP00000010200 | ENSOCUP00000006164 | Apoptotic peptidase activating factor 1. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.833 |
| APAF1 | TRADD | ENSOCUP00000010200 | ENSOCUP00000018718 | Apoptotic peptidase activating factor 1. | TNFRSF1A associated via death domain. | 0.584 |
| BCAP31 | CASP8 | ENSOCUP00000015397 | ENSOCUP00000049942 | B cell receptor associated protein 31. | DED domain-containing protein. | 0.485 |
| BCAP31 | G1SSE7_RABIT | ENSOCUP00000015397 | ENSOCUP00000006164 | B cell receptor associated protein 31. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.745 |
| CASP3 | APAF1 | ENSOCUP00000036614 | ENSOCUP00000010200 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Apoptotic peptidase activating factor 1. | 0.998 |
| CASP3 | CASP8 | ENSOCUP00000036614 | ENSOCUP00000049942 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | DED domain-containing protein. | 0.999 |
| CASP3 | CFLAR | ENSOCUP00000036614 | ENSOCUP00000009525 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | 0.435 |
| CASP3 | FAS | ENSOCUP00000036614 | ENSOCUP00000033980 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Uncharacterized protein. | 0.778 |
| CASP3 | FASLG | ENSOCUP00000036614 | ENSOCUP00000022211 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Fas ligand; Belongs to the tumor necrosis factor family. | 0.829 |
| CASP3 | G1SSE7_RABIT | ENSOCUP00000036614 | ENSOCUP00000006164 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.823 |
| CASP3 | RIPK1 | ENSOCUP00000036614 | ENSOCUP00000010138 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Receptor interacting serine/threonine kinase 1. | 0.914 |
| CASP3 | TRADD | ENSOCUP00000036614 | ENSOCUP00000018718 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | TNFRSF1A associated via death domain. | 0.831 |
| CASP3 | TRAF1 | ENSOCUP00000036614 | ENSOCUP00000004916 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | TNF receptor-associated factor. | 0.684 |
| CASP8 | APAF1 | ENSOCUP00000049942 | ENSOCUP00000010200 | DED domain-containing protein. | Apoptotic peptidase activating factor 1. | 0.977 |
| CASP8 | BCAP31 | ENSOCUP00000049942 | ENSOCUP00000015397 | DED domain-containing protein. | B cell receptor associated protein 31. | 0.485 |
| CASP8 | CASP3 | ENSOCUP00000049942 | ENSOCUP00000036614 | DED domain-containing protein. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | 0.999 |