ABL1 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABI1	ABL1	ENSOCUP00000008681	ENSOCUP00000038489	Abl interactor 1.	Tyrosine-protein kinase.	0.934
ABI1	CBL	ENSOCUP00000008681	ENSOCUP00000004160	Abl interactor 1.	Cbl proto-oncogene.	0.497
ABI1	CRKL	ENSOCUP00000008681	ENSOCUP00000000710	Abl interactor 1.	CRK like proto-oncogene, adaptor protein.	0.841
ABI1	ENAH	ENSOCUP00000008681	ENSOCUP00000001984	Abl interactor 1.	ENAH actin regulator.	0.779
ABI1	GRB2	ENSOCUP00000008681	ENSOCUP00000042433	Abl interactor 1.	Growth factor receptor bound protein 2.	0.705
ABL1	ABI1	ENSOCUP00000038489	ENSOCUP00000008681	Tyrosine-protein kinase.	Abl interactor 1.	0.934
ABL1	ATM	ENSOCUP00000038489	ENSOCUP00000012638	Tyrosine-protein kinase.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.949
ABL1	BCR	ENSOCUP00000038489	ENSOCUP00000027066	Tyrosine-protein kinase.	BCR activator of RhoGEF and GTPase.	0.981
ABL1	CBL	ENSOCUP00000038489	ENSOCUP00000004160	Tyrosine-protein kinase.	Cbl proto-oncogene.	0.911
ABL1	CRKL	ENSOCUP00000038489	ENSOCUP00000000710	Tyrosine-protein kinase.	CRK like proto-oncogene, adaptor protein.	0.971
ABL1	ENAH	ENSOCUP00000038489	ENSOCUP00000001984	Tyrosine-protein kinase.	ENAH actin regulator.	0.873
ABL1	GRB2	ENSOCUP00000038489	ENSOCUP00000042433	Tyrosine-protein kinase.	Growth factor receptor bound protein 2.	0.921
ABL1	RB1	ENSOCUP00000038489	ENSOCUP00000041017	Tyrosine-protein kinase.	RB transcriptional corepressor 1.	0.906
ABL1	SHC1	ENSOCUP00000038489	ENSOCUP00000013916	Tyrosine-protein kinase.	SHC adaptor protein 1.	0.881
ABL1	SHC3	ENSOCUP00000038489	ENSOCUP00000039863	Tyrosine-protein kinase.	SHC adaptor protein 3.	0.852
ATM	ABL1	ENSOCUP00000012638	ENSOCUP00000038489	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Tyrosine-protein kinase.	0.949
BCR	ABL1	ENSOCUP00000027066	ENSOCUP00000038489	BCR activator of RhoGEF and GTPase.	Tyrosine-protein kinase.	0.981
BCR	CBL	ENSOCUP00000027066	ENSOCUP00000004160	BCR activator of RhoGEF and GTPase.	Cbl proto-oncogene.	0.978
BCR	CRKL	ENSOCUP00000027066	ENSOCUP00000000710	BCR activator of RhoGEF and GTPase.	CRK like proto-oncogene, adaptor protein.	0.987
BCR	GRB2	ENSOCUP00000027066	ENSOCUP00000042433	BCR activator of RhoGEF and GTPase.	Growth factor receptor bound protein 2.	0.994