STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (938 aa)    
Predicted Functional Partners:
CLPX
Caseinolytic mitochondrial matrix peptidase chaperone subunit.
 
 
 0.907
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.822
CLPP
ATP-dependent Clp protease proteolytic subunit.
  
 
 0.810
G1U2E4_RABIT
Uncharacterized protein.
 
    
 0.737
PEX5
Peroxisomal biogenesis factor 5.
   
 0.733
AFG3L2
AFG3 like matrix AAA peptidase subunit 2.
  
 
 0.711
VARS1
Valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.704
SRFBP1
Serum response factor binding protein 1.
  
  
 0.699
PEX13
Peroxisomal biogenesis factor 13.
   
 
 0.690
PEX5L
Peroxisomal biogenesis factor 5 like.
   
 0.690
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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