STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLCN6Chloride transport protein 6; Chloride transport protein, initially identified as voltage- gated chloride channel. The presence of the conserved gating glutamate residues suggests that is functions as antiporter (By similarity). Belongs to the chloride channel (TC 2.A.49) family. ClC- 6/CLCN6 subfamily. (870 aa)    
Predicted Functional Partners:
OSTM1
Uncharacterized protein.
   
 0.996
FAM131B
Family with sequence similarity 131 member B.
   
 
 0.783
MKRN1
Makorin ring finger protein 1.
      
 0.666
OCRL
OCRL inositol polyphosphate-5-phosphatase.
   
  
 0.629
MED19
Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.620
CHRNG
Cholinergic receptor nicotinic gamma subunit.
      
 0.619
GPR89B
Uncharacterized protein.
   
  
 0.610
KIAA1549
KIAA1549.
     
 0.599
PRPF3
Pre-mRNA processing factor 3.
      
 0.591
CLCA2
Chloride channel accessory 2.
   
 
 0.584
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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