IKZF2 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

IKZF2

IKAROS family zinc finger 2. (540 aa)

Predicted Functional Partners:

FOXP3

0.682

TIGIT

0.603

CRBN

0.603

IKZF1

0.580

CTLA4

0.573

GATA3

0.540

VWC2L

0.527

SLC26A5

0.524

RUNX1

0.524

ITGAE

0.523

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRBN	IKZF1	ENSOCUP00000033173	ENSOCUP00000012401	Cereblon.	IKAROS family zinc finger 1.	0.996
CRBN	IKZF2	ENSOCUP00000033173	ENSOCUP00000006320	Cereblon.	IKAROS family zinc finger 2.	0.603
CTLA4	FOXP3	ENSOCUP00000017677	ENSOCUP00000008733	Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.	Forkhead box P3.	0.934
CTLA4	GATA3	ENSOCUP00000017677	ENSOCUP00000015302	Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.	GATA binding protein 3.	0.644
CTLA4	IKZF2	ENSOCUP00000017677	ENSOCUP00000006320	Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.	IKAROS family zinc finger 2.	0.573
CTLA4	ITGAE	ENSOCUP00000017677	ENSOCUP00000042615	Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.	Integrin subunit alpha E; Belongs to the integrin alpha chain family.	0.550
CTLA4	TIGIT	ENSOCUP00000017677	ENSOCUP00000003654	Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.	T cell immunoreceptor with Ig and ITIM domains.	0.876
FOXP3	CTLA4	ENSOCUP00000008733	ENSOCUP00000017677	Forkhead box P3.	Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.	0.934
FOXP3	GATA3	ENSOCUP00000008733	ENSOCUP00000015302	Forkhead box P3.	GATA binding protein 3.	0.890
FOXP3	IKZF1	ENSOCUP00000008733	ENSOCUP00000012401	Forkhead box P3.	IKAROS family zinc finger 1.	0.423
FOXP3	IKZF2	ENSOCUP00000008733	ENSOCUP00000006320	Forkhead box P3.	IKAROS family zinc finger 2.	0.682
FOXP3	ITGAE	ENSOCUP00000008733	ENSOCUP00000042615	Forkhead box P3.	Integrin subunit alpha E; Belongs to the integrin alpha chain family.	0.571
FOXP3	RUNX1	ENSOCUP00000008733	ENSOCUP00000011814	Forkhead box P3.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.750
FOXP3	TIGIT	ENSOCUP00000008733	ENSOCUP00000003654	Forkhead box P3.	T cell immunoreceptor with Ig and ITIM domains.	0.764
GATA3	CTLA4	ENSOCUP00000015302	ENSOCUP00000017677	GATA binding protein 3.	Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.	0.644
GATA3	FOXP3	ENSOCUP00000015302	ENSOCUP00000008733	GATA binding protein 3.	Forkhead box P3.	0.890
GATA3	IKZF1	ENSOCUP00000015302	ENSOCUP00000012401	GATA binding protein 3.	IKAROS family zinc finger 1.	0.535
GATA3	IKZF2	ENSOCUP00000015302	ENSOCUP00000006320	GATA binding protein 3.	IKAROS family zinc finger 2.	0.540
GATA3	RUNX1	ENSOCUP00000015302	ENSOCUP00000011814	GATA binding protein 3.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.922
GATA3	TIGIT	ENSOCUP00000015302	ENSOCUP00000003654	GATA binding protein 3.	T cell immunoreceptor with Ig and ITIM domains.	0.472