Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)    
Predicted Functional Partners:
GSR
Glutathione-disulfide reductase.
  
 0.964
PRDX6
Thioredoxin domain-containing protein.
   
 0.961
GPX2
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 
0.930
MGST1
Microsomal glutathione S-transferase 1.
   
 
 0.917
ALOX15
Arachidonate 15-lipoxygenase; Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12- HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the o [...]
     
 0.914
LOC100349830
DSBA domain-containing protein.
    
 0.912
GSTP1
Uncharacterized protein.
   
 
 0.909
GSTM3
Glutathione S-transferase.
   
 
 0.903
HPGDS
Hematopoietic prostaglandin D synthase.
   
 
 0.903
GPX3
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
  
0.900
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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