| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGRP | GHRH | ENSOCUP00000010187 | ENSOCUP00000005058 | Agouti related neuropeptide. | Growth hormone releasing hormone. | 0.829 |
| AGRP | GHRL | ENSOCUP00000010187 | ENSOCUP00000029787 | Agouti related neuropeptide. | Uncharacterized protein. | 0.935 |
| AGRP | GHSR | ENSOCUP00000010187 | ENSOCUP00000006345 | Agouti related neuropeptide. | Growth hormone secretagogue receptor type 1; Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK- 0677, adenosine) (By similarity). | 0.799 |
| AGRP | NPY | ENSOCUP00000010187 | ENSOCUP00000009261 | Agouti related neuropeptide. | Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | 0.985 |
| AGRP | SST | ENSOCUP00000010187 | ENSOCUP00000006540 | Agouti related neuropeptide. | Somatostatin. | 0.553 |
| EDN1 | GHRL | ENSOCUP00000011526 | ENSOCUP00000029787 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | Uncharacterized protein. | 0.467 |
| EDN1 | GHSR | ENSOCUP00000011526 | ENSOCUP00000006345 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | Growth hormone secretagogue receptor type 1; Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK- 0677, adenosine) (By similarity). | 0.786 |
| EDN1 | GNAI1 | ENSOCUP00000011526 | ENSOCUP00000000882 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | G protein subunit alpha i1. | 0.403 |
| EDN1 | GNAQ | ENSOCUP00000011526 | ENSOCUP00000014234 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | G protein subunit alpha q. | 0.456 |
| EDN1 | NPY | ENSOCUP00000011526 | ENSOCUP00000009261 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | 0.426 |
| GHRH | AGRP | ENSOCUP00000005058 | ENSOCUP00000010187 | Growth hormone releasing hormone. | Agouti related neuropeptide. | 0.829 |
| GHRH | GHRL | ENSOCUP00000005058 | ENSOCUP00000029787 | Growth hormone releasing hormone. | Uncharacterized protein. | 0.873 |
| GHRH | GHSR | ENSOCUP00000005058 | ENSOCUP00000006345 | Growth hormone releasing hormone. | Growth hormone secretagogue receptor type 1; Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK- 0677, adenosine) (By similarity). | 0.875 |
| GHRH | NPY | ENSOCUP00000005058 | ENSOCUP00000009261 | Growth hormone releasing hormone. | Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | 0.724 |
| GHRH | SST | ENSOCUP00000005058 | ENSOCUP00000006540 | Growth hormone releasing hormone. | Somatostatin. | 0.905 |
| GHRL | AGRP | ENSOCUP00000029787 | ENSOCUP00000010187 | Uncharacterized protein. | Agouti related neuropeptide. | 0.935 |
| GHRL | EDN1 | ENSOCUP00000029787 | ENSOCUP00000011526 | Uncharacterized protein. | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | 0.467 |
| GHRL | GHRH | ENSOCUP00000029787 | ENSOCUP00000005058 | Uncharacterized protein. | Growth hormone releasing hormone. | 0.873 |
| GHRL | GHSR | ENSOCUP00000029787 | ENSOCUP00000006345 | Uncharacterized protein. | Growth hormone secretagogue receptor type 1; Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK- 0677, adenosine) (By similarity). | 0.999 |
| GHRL | GNAQ | ENSOCUP00000029787 | ENSOCUP00000014234 | Uncharacterized protein. | G protein subunit alpha q. | 0.400 |