PTS protein (Oryctolagus cuniculus) - STRING interaction network

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Score

PTS

6-pyruvoyl tetrahydrobiopterin synthase. (146 aa)

Predicted Functional Partners:

SPR

0.995

GCH1

0.993

CBR1

0.930

G1TLJ2_RABIT

0.924

LOC100348029

0.924

G1U2X0_RABIT

0.924

ENSOCUP00000036860

0.912

AKR1B10

0.901

AKR1B1

0.901

G1SXE4_RABIT

0.900

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKR1B1	AKR1B10	ENSOCUP00000028417	ENSOCUP00000020925	Aldo-keto reductase family 1 member B1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.	Aldo_ket_red domain-containing protein.	0.926
AKR1B1	CBR1	ENSOCUP00000028417	ENSOCUP00000016888	Aldo-keto reductase family 1 member B1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity).	0.959
AKR1B1	G1TLJ2_RABIT	ENSOCUP00000028417	ENSOCUP00000017843	Aldo-keto reductase family 1 member B1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.949
AKR1B1	G1U2X0_RABIT	ENSOCUP00000028417	ENSOCUP00000023724	Aldo-keto reductase family 1 member B1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.949
AKR1B1	LOC100348029	ENSOCUP00000028417	ENSOCUP00000018584	Aldo-keto reductase family 1 member B1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.949
AKR1B1	PTS	ENSOCUP00000028417	ENSOCUP00000006362	Aldo-keto reductase family 1 member B1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.	6-pyruvoyl tetrahydrobiopterin synthase.	0.901
AKR1B1	SPR	ENSOCUP00000028417	ENSOCUP00000000728	Aldo-keto reductase family 1 member B1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.	Sepiapterin reductase.	0.934
AKR1B10	AKR1B1	ENSOCUP00000020925	ENSOCUP00000028417	Aldo_ket_red domain-containing protein.	Aldo-keto reductase family 1 member B1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.	0.926
AKR1B10	CBR1	ENSOCUP00000020925	ENSOCUP00000016888	Aldo_ket_red domain-containing protein.	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity).	0.959
AKR1B10	G1TLJ2_RABIT	ENSOCUP00000020925	ENSOCUP00000017843	Aldo_ket_red domain-containing protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.941
AKR1B10	G1U2X0_RABIT	ENSOCUP00000020925	ENSOCUP00000023724	Aldo_ket_red domain-containing protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.941
AKR1B10	LOC100348029	ENSOCUP00000020925	ENSOCUP00000018584	Aldo_ket_red domain-containing protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.941
AKR1B10	PTS	ENSOCUP00000020925	ENSOCUP00000006362	Aldo_ket_red domain-containing protein.	6-pyruvoyl tetrahydrobiopterin synthase.	0.901
AKR1B10	SPR	ENSOCUP00000020925	ENSOCUP00000000728	Aldo_ket_red domain-containing protein.	Sepiapterin reductase.	0.920
CBR1	AKR1B1	ENSOCUP00000016888	ENSOCUP00000028417	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity).	Aldo-keto reductase family 1 member B1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.	0.959
CBR1	AKR1B10	ENSOCUP00000016888	ENSOCUP00000020925	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity).	Aldo_ket_red domain-containing protein.	0.959
CBR1	G1TLJ2_RABIT	ENSOCUP00000016888	ENSOCUP00000017843	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity).	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.900
CBR1	G1U2X0_RABIT	ENSOCUP00000016888	ENSOCUP00000023724	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity).	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.900
CBR1	LOC100348029	ENSOCUP00000016888	ENSOCUP00000018584	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity).	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.900
CBR1	PTS	ENSOCUP00000016888	ENSOCUP00000006362	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity).	6-pyruvoyl tetrahydrobiopterin synthase.	0.930