STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENDOUEndonuclease, poly(U) specific. (369 aa)    
Predicted Functional Partners:
CLPTM1L
CLPTM1 like.
      
 0.697
PAMR1
Peptidase domain containing associated with muscle regeneration 1; Belongs to the peptidase S1 family.
      
 0.622
SYCP2
Synaptonemal complex protein 2.
      
 0.596
PPP1CC
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin de [...]
   
  
 0.576
MAVS
Mitochondrial antiviral signaling protein.
      
 0.533
PDE12
Phosphodiesterase 12.
      
 0.530
CXCL10
C-X-C motif chemokine.
      
 0.489
TMEM79
Uncharacterized protein.
   
  
 0.485
RNASEL
Uncharacterized protein.
   
  
 0.477
BNIPL
BCL2 interacting protein like.
   
  
 0.466
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.