C3AR1 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

C3AR1

Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (480 aa)

Predicted Functional Partners:

C1QB

0.783

C1QA

0.775

C5

0.755

C5AR1

0.741

ITGB2

0.715

ENSOCUP00000027220

0.710

C4A

0.690

CYBB

0.679

XK

0.648

C3

0.640

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1QA	C1QB	ENSOCUP00000026373	ENSOCUP00000044926	Complement C1q A chain.	Complement C1q B chain.	0.990
C1QA	C3	ENSOCUP00000026373	ENSOCUP00000006634	Complement C1q A chain.	Complement C3 alpha chain; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.	0.498
C1QA	C3AR1	ENSOCUP00000026373	ENSOCUP00000006429	Complement C1q A chain.	Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.775
C1QA	C4A	ENSOCUP00000026373	ENSOCUP00000006093	Complement C1q A chain.	Uncharacterized protein.	0.689
C1QA	C5AR1	ENSOCUP00000026373	ENSOCUP00000023879	Complement C1q A chain.	C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N- terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (By similarity).	0.737
C1QA	CYBB	ENSOCUP00000026373	ENSOCUP00000035279	Complement C1q A chain.	FAD-binding FR-type domain-containing protein.	0.523
C1QA	ITGB2	ENSOCUP00000026373	ENSOCUP00000040076	Complement C1q A chain.	Integrin beta.	0.594
C1QA	XK	ENSOCUP00000026373	ENSOCUP00000005673	Complement C1q A chain.	XK-related protein.	0.478
C1QB	C1QA	ENSOCUP00000044926	ENSOCUP00000026373	Complement C1q B chain.	Complement C1q A chain.	0.990
C1QB	C3	ENSOCUP00000044926	ENSOCUP00000006634	Complement C1q B chain.	Complement C3 alpha chain; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.	0.530
C1QB	C3AR1	ENSOCUP00000044926	ENSOCUP00000006429	Complement C1q B chain.	Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.783
C1QB	C4A	ENSOCUP00000044926	ENSOCUP00000006093	Complement C1q B chain.	Uncharacterized protein.	0.731
C1QB	C5AR1	ENSOCUP00000044926	ENSOCUP00000023879	Complement C1q B chain.	C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N- terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (By similarity).	0.730
C1QB	CYBB	ENSOCUP00000044926	ENSOCUP00000035279	Complement C1q B chain.	FAD-binding FR-type domain-containing protein.	0.474
C1QB	ITGB2	ENSOCUP00000044926	ENSOCUP00000040076	Complement C1q B chain.	Integrin beta.	0.744
C1QB	XK	ENSOCUP00000044926	ENSOCUP00000005673	Complement C1q B chain.	XK-related protein.	0.456
C3	C1QA	ENSOCUP00000006634	ENSOCUP00000026373	Complement C3 alpha chain; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.	Complement C1q A chain.	0.498
C3	C1QB	ENSOCUP00000006634	ENSOCUP00000044926	Complement C3 alpha chain; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.	Complement C1q B chain.	0.530
C3	C3AR1	ENSOCUP00000006634	ENSOCUP00000006429	Complement C3 alpha chain; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.	Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.640
C3	C5	ENSOCUP00000006634	ENSOCUP00000004927	Complement C3 alpha chain; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.	Complement C5.	0.579