Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C3AR1Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (480 aa)    
Predicted Functional Partners:
C4A
Uncharacterized protein.
    
 0.912
C3
Complement C3 alpha chain; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
    
 0.889
LOC100346672
Uncharacterized protein.
    
 0.889
C5
Complement C5.
    
 0.838
ENSOCUP00000027220
Anaphylatoxin-like domain-containing protein.
    
 0.814
C1QB
Complement C1q B chain.
   
 
 0.775
C1QA
Complement C1q A chain.
   
 
 0.761
GNB4
G protein subunit beta 4.
   
 0.639
GNB1
G protein subunit beta 1.
   
 0.639
LOC100348748
IGv domain-containing protein.
   
  
 0.628
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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