STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMNB1Lamin B1; Belongs to the intermediate filament family. (609 aa)    
Predicted Functional Partners:
LMNA
Lamin A/C; Belongs to the intermediate filament family.
    
0.995
LBR
Lamin B receptor.
   
 
 0.980
CASP6
Caspase 6; Belongs to the phospholipase A2 family.
   
 0.976
EMD
Emerin (Predicted).
   
 0.962
BANF1
Uncharacterized protein.
   
 0.949
LOC103351183
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.912
BANF2
Barrier to autointegration factor 2.
   
 0.910
SUN2
Sad1 and UNC84 domain containing 2.
    
 0.909
GAPDH
Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]
   
 
 0.855
SYNE2
KASH domain-containing protein.
    
 0.851
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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