LRIG1 protein (Oryctolagus cuniculus) - STRING interaction network

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Predicted Interactions

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Score

LRIG1

Leucine rich repeats and immunoglobulin like domains 1. (1154 aa)

Predicted Functional Partners:

MST1R

0.953

MET

0.947

EGFR

0.913

HOPX

0.784

BMI1

0.760

ADGRL2

0.713

ADGRL1

0.704

ADGRL3

0.704

ERBB2

0.653

EGF

0.653

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRL1	LRIG1	ENSOCUP00000023951	ENSOCUP00000006502	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeats and immunoglobulin like domains 1.	0.704
ADGRL2	LRIG1	ENSOCUP00000044036	ENSOCUP00000006502	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeats and immunoglobulin like domains 1.	0.713
ADGRL3	LRIG1	ENSOCUP00000030893	ENSOCUP00000006502	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeats and immunoglobulin like domains 1.	0.704
BMI1	EGF	ENSOCUP00000004703	ENSOCUP00000014095	RING-type domain-containing protein.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.661
BMI1	EGFR	ENSOCUP00000004703	ENSOCUP00000009041	RING-type domain-containing protein.	Receptor protein-tyrosine kinase.	0.500
BMI1	HOPX	ENSOCUP00000004703	ENSOCUP00000004422	RING-type domain-containing protein.	Homeobox domain-containing protein.	0.703
BMI1	LRIG1	ENSOCUP00000004703	ENSOCUP00000006502	RING-type domain-containing protein.	Leucine rich repeats and immunoglobulin like domains 1.	0.760
EGF	BMI1	ENSOCUP00000014095	ENSOCUP00000004703	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	RING-type domain-containing protein.	0.661
EGF	EGFR	ENSOCUP00000014095	ENSOCUP00000009041	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.999
EGF	ERBB2	ENSOCUP00000014095	ENSOCUP00000009117	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.998
EGF	LRIG1	ENSOCUP00000014095	ENSOCUP00000006502	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Leucine rich repeats and immunoglobulin like domains 1.	0.653
EGF	MET	ENSOCUP00000014095	ENSOCUP00000003111	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.811
EGF	MST1R	ENSOCUP00000014095	ENSOCUP00000008078	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Macrophage stimulating 1 receptor.	0.429
EGFR	BMI1	ENSOCUP00000009041	ENSOCUP00000004703	Receptor protein-tyrosine kinase.	RING-type domain-containing protein.	0.500
EGFR	EGF	ENSOCUP00000009041	ENSOCUP00000014095	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.999
EGFR	ERBB2	ENSOCUP00000009041	ENSOCUP00000009117	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.999
EGFR	LRIG1	ENSOCUP00000009041	ENSOCUP00000006502	Receptor protein-tyrosine kinase.	Leucine rich repeats and immunoglobulin like domains 1.	0.913
EGFR	MET	ENSOCUP00000009041	ENSOCUP00000003111	Receptor protein-tyrosine kinase.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.835
EGFR	MST1R	ENSOCUP00000009041	ENSOCUP00000008078	Receptor protein-tyrosine kinase.	Macrophage stimulating 1 receptor.	0.844
ERBB2	EGF	ENSOCUP00000009117	ENSOCUP00000014095	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.998