ENSOCUP00000006516 protein (Oryctolagus cuniculus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ENSOCUP00000006516

Peptidyl-prolyl cis-trans isomerase FKBP3. (390 aa)

Predicted Functional Partners:

MTOR

0.720

G1TTB9_RABIT

0.677

RPS15

0.633

LOC100338745

0.562

RPL18A

0.545

SMG1

0.541

ENSOCUP00000027928

0.539

EIF4E1B

0.539

EIF4E

0.539

ATP6V0C

0.535

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V0C	ENSOCUP00000006516	ENSOCUP00000006154	ENSOCUP00000006516	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Peptidyl-prolyl cis-trans isomerase FKBP3.	0.535
ATP6V0C	G1TTB9_RABIT	ENSOCUP00000006154	ENSOCUP00000020289	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.472
ATP6V0C	MTOR	ENSOCUP00000006154	ENSOCUP00000011253	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.668
ATP6V0C	RPS15	ENSOCUP00000006154	ENSOCUP00000022933	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.	0.517
ATP6V0C	SMG1	ENSOCUP00000006154	ENSOCUP00000014295	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.	0.499
EIF4E	EIF4E1B	ENSOCUP00000032078	ENSOCUP00000029008	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family.	0.979
EIF4E	ENSOCUP00000006516	ENSOCUP00000032078	ENSOCUP00000006516	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	Peptidyl-prolyl cis-trans isomerase FKBP3.	0.539
EIF4E	ENSOCUP00000027928	ENSOCUP00000032078	ENSOCUP00000027928	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.542
EIF4E	MTOR	ENSOCUP00000032078	ENSOCUP00000011253	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.961
EIF4E	RPS15	ENSOCUP00000032078	ENSOCUP00000022933	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.	0.420
EIF4E	SMG1	ENSOCUP00000032078	ENSOCUP00000014295	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.	0.722
EIF4E1B	EIF4E	ENSOCUP00000029008	ENSOCUP00000032078	Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family.	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	0.979
EIF4E1B	ENSOCUP00000006516	ENSOCUP00000029008	ENSOCUP00000006516	Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family.	Peptidyl-prolyl cis-trans isomerase FKBP3.	0.539
EIF4E1B	ENSOCUP00000027928	ENSOCUP00000029008	ENSOCUP00000027928	Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.945
EIF4E1B	MTOR	ENSOCUP00000029008	ENSOCUP00000011253	Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.752
EIF4E1B	SMG1	ENSOCUP00000029008	ENSOCUP00000014295	Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family.	SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.	0.578
ENSOCUP00000006516	ATP6V0C	ENSOCUP00000006516	ENSOCUP00000006154	Peptidyl-prolyl cis-trans isomerase FKBP3.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.535
ENSOCUP00000006516	EIF4E	ENSOCUP00000006516	ENSOCUP00000032078	Peptidyl-prolyl cis-trans isomerase FKBP3.	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	0.539
ENSOCUP00000006516	EIF4E1B	ENSOCUP00000006516	ENSOCUP00000029008	Peptidyl-prolyl cis-trans isomerase FKBP3.	Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family.	0.539
ENSOCUP00000006516	ENSOCUP00000027928	ENSOCUP00000006516	ENSOCUP00000027928	Peptidyl-prolyl cis-trans isomerase FKBP3.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.539