GPR135 protein (Oryctolagus cuniculus) - STRING interaction network

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GPR135

G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family. (380 aa)

Predicted Functional Partners:

GPR162

0.661

GPR142

0.657

ARRB1

0.588

NPFF

0.574

RLN3

0.532

SAG

0.527

ARR3

0.527

RCVRN

0.512

PTAFR

0.500

GNB4

0.498

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARR3	GPR135	ENSOCUP00000014674	ENSOCUP00000006525	Arrestin 3.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.527
ARR3	RCVRN	ENSOCUP00000014674	ENSOCUP00000013316	Arrestin 3.	Recoverin.	0.753
ARRB1	GPR135	ENSOCUP00000019641	ENSOCUP00000006525	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.588
ARRB1	PTAFR	ENSOCUP00000019641	ENSOCUP00000015312	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Platelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family.	0.435
GNB4	GPR135	ENSOCUP00000000803	ENSOCUP00000006525	G protein subunit beta 4.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.498
GPR135	ARR3	ENSOCUP00000006525	ENSOCUP00000014674	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Arrestin 3.	0.527
GPR135	ARRB1	ENSOCUP00000006525	ENSOCUP00000019641	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.588
GPR135	GNB4	ENSOCUP00000006525	ENSOCUP00000000803	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 4.	0.498
GPR135	GPR142	ENSOCUP00000006525	ENSOCUP00000022297	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 142; Belongs to the G-protein coupled receptor 1 family.	0.657
GPR135	GPR162	ENSOCUP00000006525	ENSOCUP00000049906	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 162.	0.661
GPR135	NPFF	ENSOCUP00000006525	ENSOCUP00000025285	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Neuropeptide FF-amide peptide precursor.	0.574
GPR135	PTAFR	ENSOCUP00000006525	ENSOCUP00000015312	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Platelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family.	0.500
GPR135	RCVRN	ENSOCUP00000006525	ENSOCUP00000013316	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Recoverin.	0.512
GPR135	RLN3	ENSOCUP00000006525	ENSOCUP00000011573	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Relaxin 3.	0.532
GPR135	SAG	ENSOCUP00000006525	ENSOCUP00000013144	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	S-antigen visual arrestin.	0.527
GPR142	GPR135	ENSOCUP00000022297	ENSOCUP00000006525	G protein-coupled receptor 142; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.657
GPR162	GPR135	ENSOCUP00000049906	ENSOCUP00000006525	G protein-coupled receptor 162.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.661
NPFF	GPR135	ENSOCUP00000025285	ENSOCUP00000006525	Neuropeptide FF-amide peptide precursor.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.574
PTAFR	ARRB1	ENSOCUP00000015312	ENSOCUP00000019641	Platelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.435
PTAFR	GPR135	ENSOCUP00000015312	ENSOCUP00000006525	Platelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.500