GPR135 protein (Oryctolagus cuniculus) - STRING interaction network

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GPR135

G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family. (380 aa)

Predicted Functional Partners:

NPFF

0.865

NPVF

0.730

TAAR9

0.627

GNB2

0.622

ARRB1

0.608

ARR3

0.580

SAG

0.575

PLCL2

0.571

GPR173

0.549

GPR158

0.533

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARR3	GNB2	ENSOCUP00000014674	ENSOCUP00000042929	Arrestin 3.	G protein subunit beta 2.	0.455
ARR3	GPR135	ENSOCUP00000014674	ENSOCUP00000006525	Arrestin 3.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.580
ARRB1	GNB2	ENSOCUP00000019641	ENSOCUP00000042929	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	G protein subunit beta 2.	0.455
ARRB1	GPR135	ENSOCUP00000019641	ENSOCUP00000006525	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.608
GNB2	ARR3	ENSOCUP00000042929	ENSOCUP00000014674	G protein subunit beta 2.	Arrestin 3.	0.455
GNB2	ARRB1	ENSOCUP00000042929	ENSOCUP00000019641	G protein subunit beta 2.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.455
GNB2	GPR135	ENSOCUP00000042929	ENSOCUP00000006525	G protein subunit beta 2.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.622
GNB2	PLCL2	ENSOCUP00000042929	ENSOCUP00000033423	G protein subunit beta 2.	Phosphoinositide phospholipase C.	0.400
GNB2	SAG	ENSOCUP00000042929	ENSOCUP00000013144	G protein subunit beta 2.	S-antigen visual arrestin.	0.447
GPR135	ARR3	ENSOCUP00000006525	ENSOCUP00000014674	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Arrestin 3.	0.580
GPR135	ARRB1	ENSOCUP00000006525	ENSOCUP00000019641	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.608
GPR135	GNB2	ENSOCUP00000006525	ENSOCUP00000042929	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 2.	0.622
GPR135	GPR158	ENSOCUP00000006525	ENSOCUP00000004647	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 158.	0.533
GPR135	GPR173	ENSOCUP00000006525	ENSOCUP00000015884	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 173.	0.549
GPR135	NPFF	ENSOCUP00000006525	ENSOCUP00000025285	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Neuropeptide FF-amide peptide precursor.	0.865
GPR135	NPVF	ENSOCUP00000006525	ENSOCUP00000008220	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Neuropeptide VF precursor.	0.730
GPR135	PLCL2	ENSOCUP00000006525	ENSOCUP00000033423	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Phosphoinositide phospholipase C.	0.571
GPR135	SAG	ENSOCUP00000006525	ENSOCUP00000013144	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	S-antigen visual arrestin.	0.575
GPR135	TAAR9	ENSOCUP00000006525	ENSOCUP00000007155	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Trace amine associated receptor 9 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family.	0.627
GPR158	GPR135	ENSOCUP00000004647	ENSOCUP00000006525	G protein-coupled receptor 158.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.533