STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRPV6ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (699 aa)    
Predicted Functional Partners:
TRPM8
Transient receptor potential cation channel subfamily M member 8.
   
 
 0.827
TRPM7
Transient receptor potential cation channel subfamily M member 7.
   
 
 0.817
TRPC1
Short transient receptor potential channel 1; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G- protein coupled receptors. Seems to be also activated by intracellular calcium store depletion; Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
     
 0.799
S100a10
Protein S100-A10; Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.
    
 
 0.772
TRPM6
Transient receptor potential cation channel subfamily M member 6.
   
 
 0.772
TRPC6
Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family.
     
 0.758
CALM1
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).
    
 
 0.733
TRPC4
Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family.
     
 0.718
TRPC3
Transient receptor potential cation channel subfamily C member 3.
     
 0.718
S100G
Protein S100; Belongs to the S-100 family.
     
 0.715
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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