Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLHL3Kelch like family member 3. (605 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.990
WNK4
WNK lysine deficient protein kinase 4.
    
 
 0.983
WNK1
WNK lysine deficient protein kinase 1.
    
 
 0.978
WNK3
WNK lysine deficient protein kinase 3.
    
 
 0.883
KEAP1
Kelch like ECH associated protein 1.
  
 
0.854
KLHL2
Kelch like family member 2.
    
  0.824
FBXL17
Uncharacterized protein.
    
 0.792
KLHL12
Kelch like family member 12.
    
   0.772
NANP
N-acetylneuraminic acid phosphatase.
   
 
 0.735
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.734
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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