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ACTC1 protein (Oryctolagus cuniculus) - STRING interaction network
"ACTC1" - Actin, alpha skeletal muscle in Oryctolagus cuniculus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ACTC1Actin, alpha skeletal muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells (377 aa)    
Predicted Functional Partners:
TPM3
Tropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments; Belongs to the tropomyosin family (283 aa)
     
  0.993
MYH7
Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family (1934 aa)
     
  0.976
MYL2
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] (166 aa)
     
  0.961
TPM4
Tropomyosin 4; Belongs to the tropomyosin family (284 aa)
     
  0.958
MYL3
Myosin, light chain 3, alkali; ventricular, skeletal, slow (209 aa)
     
  0.949
PFN1
Profilin 1; Belongs to the profilin family (98 aa)
     
 
  0.934
WASL
Wiskott-Aldrich syndrome-like (512 aa)
       
 
  0.927
MYLPF
Myosin light chain, phosphorylatable, fast skeletal muscle (150 aa)
     
 
  0.925
ENSOCUG00000007222
annotation not available (247 aa)
     
  0.921
WAS
Wiskott-Aldrich syndrome (485 aa)
       
 
  0.912
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, Oryctolagus cuniculus, domestic rabbit, rabbit, rabbits
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