KHDRBS1 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

KHDRBS1

KH RNA binding domain containing, signal transduction associated 1. (443 aa)

Predicted Functional Partners:

FYN

0.938

APC

0.835

RASA1

0.829

GRB2

0.795

PRMT1

0.759

FGR

0.753

DHX9

0.753

FUBP3

0.730

HNRNPK

0.725

PLCG1

0.722

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APC	KHDRBS1	ENSOCUP00000013423	ENSOCUP00000006621	APC regulator of WNT signaling pathway.	KH RNA binding domain containing, signal transduction associated 1.	0.835
DHX9	HNRNPK	ENSOCUP00000029909	ENSOCUP00000008932	DExH-box helicase 9.	Heterogeneous nuclear ribonucleoprotein K; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is co [...]	0.771
DHX9	KHDRBS1	ENSOCUP00000029909	ENSOCUP00000006621	DExH-box helicase 9.	KH RNA binding domain containing, signal transduction associated 1.	0.753
FGR	GRB2	ENSOCUP00000007706	ENSOCUP00000042433	Tyrosine-protein kinase.	Growth factor receptor bound protein 2.	0.741
FGR	KHDRBS1	ENSOCUP00000007706	ENSOCUP00000006621	Tyrosine-protein kinase.	KH RNA binding domain containing, signal transduction associated 1.	0.753
FGR	PLCG1	ENSOCUP00000007706	ENSOCUP00000021041	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.440
FGR	RASA1	ENSOCUP00000007706	ENSOCUP00000004013	Tyrosine-protein kinase.	RAS p21 protein activator 1.	0.416
FUBP3	KHDRBS1	ENSOCUP00000005358	ENSOCUP00000006621	Far upstream element binding protein 3.	KH RNA binding domain containing, signal transduction associated 1.	0.730
FYN	GRB2	ENSOCUP00000013559	ENSOCUP00000042433	Tyrosine-protein kinase.	Growth factor receptor bound protein 2.	0.839
FYN	HNRNPK	ENSOCUP00000013559	ENSOCUP00000008932	Tyrosine-protein kinase.	Heterogeneous nuclear ribonucleoprotein K; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is co [...]	0.525
FYN	KHDRBS1	ENSOCUP00000013559	ENSOCUP00000006621	Tyrosine-protein kinase.	KH RNA binding domain containing, signal transduction associated 1.	0.938
FYN	PLCG1	ENSOCUP00000013559	ENSOCUP00000021041	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.748
FYN	RASA1	ENSOCUP00000013559	ENSOCUP00000004013	Tyrosine-protein kinase.	RAS p21 protein activator 1.	0.449
GRB2	FGR	ENSOCUP00000042433	ENSOCUP00000007706	Growth factor receptor bound protein 2.	Tyrosine-protein kinase.	0.741
GRB2	FYN	ENSOCUP00000042433	ENSOCUP00000013559	Growth factor receptor bound protein 2.	Tyrosine-protein kinase.	0.839
GRB2	KHDRBS1	ENSOCUP00000042433	ENSOCUP00000006621	Growth factor receptor bound protein 2.	KH RNA binding domain containing, signal transduction associated 1.	0.795
GRB2	PLCG1	ENSOCUP00000042433	ENSOCUP00000021041	Growth factor receptor bound protein 2.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.975
HNRNPK	DHX9	ENSOCUP00000008932	ENSOCUP00000029909	Heterogeneous nuclear ribonucleoprotein K; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is co [...]	DExH-box helicase 9.	0.771
HNRNPK	FYN	ENSOCUP00000008932	ENSOCUP00000013559	Heterogeneous nuclear ribonucleoprotein K; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is co [...]	Tyrosine-protein kinase.	0.525
HNRNPK	KHDRBS1	ENSOCUP00000008932	ENSOCUP00000006621	Heterogeneous nuclear ribonucleoprotein K; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is co [...]	KH RNA binding domain containing, signal transduction associated 1.	0.725