| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AK1 | AK4 | ENSOCUP00000040457 | ENSOCUP00000008621 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | 0.946 |
| AK1 | AK8 | ENSOCUP00000040457 | ENSOCUP00000016463 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | Adenylate kinase 8; Belongs to the adenylate kinase family. | 0.964 |
| AK1 | NME6 | ENSOCUP00000040457 | ENSOCUP00000000478 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | Nucleoside diphosphate kinase. | 0.832 |
| AK1 | THTPA | ENSOCUP00000040457 | ENSOCUP00000006669 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | Thiamine triphosphatase. | 0.935 |
| AK1 | TPK1 | ENSOCUP00000040457 | ENSOCUP00000002954 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. | 0.916 |
| AK4 | AK1 | ENSOCUP00000008621 | ENSOCUP00000040457 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | 0.946 |
| AK4 | AK8 | ENSOCUP00000008621 | ENSOCUP00000016463 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Adenylate kinase 8; Belongs to the adenylate kinase family. | 0.928 |
| AK4 | NME6 | ENSOCUP00000008621 | ENSOCUP00000000478 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Nucleoside diphosphate kinase. | 0.756 |
| AK4 | THTPA | ENSOCUP00000008621 | ENSOCUP00000006669 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Thiamine triphosphatase. | 0.919 |
| AK4 | TPK1 | ENSOCUP00000008621 | ENSOCUP00000002954 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. | 0.910 |
| AK8 | AK1 | ENSOCUP00000016463 | ENSOCUP00000040457 | Adenylate kinase 8; Belongs to the adenylate kinase family. | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | 0.964 |
| AK8 | AK4 | ENSOCUP00000016463 | ENSOCUP00000008621 | Adenylate kinase 8; Belongs to the adenylate kinase family. | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. | 0.928 |
| AK8 | NME6 | ENSOCUP00000016463 | ENSOCUP00000000478 | Adenylate kinase 8; Belongs to the adenylate kinase family. | Nucleoside diphosphate kinase. | 0.755 |
| AK8 | THTPA | ENSOCUP00000016463 | ENSOCUP00000006669 | Adenylate kinase 8; Belongs to the adenylate kinase family. | Thiamine triphosphatase. | 0.919 |
| AK8 | TPK1 | ENSOCUP00000016463 | ENSOCUP00000002954 | Adenylate kinase 8; Belongs to the adenylate kinase family. | Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. | 0.910 |
| ATP1B1 | FXYD6 | ENSOCUP00000039420 | ENSOCUP00000047203 | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. | 0.890 |
| ATP1B1 | LOC103349229 | ENSOCUP00000039420 | ENSOCUP00000047357 | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. | 0.999 |
| ATP1B1 | THTPA | ENSOCUP00000039420 | ENSOCUP00000006669 | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). | Thiamine triphosphatase. | 0.768 |
| ATP4B | FXYD6 | ENSOCUP00000021394 | ENSOCUP00000047203 | Potassium-transporting ATPase subunit beta; Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity. | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. | 0.639 |
| ATP4B | LOC103349229 | ENSOCUP00000021394 | ENSOCUP00000047357 | Potassium-transporting ATPase subunit beta; Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity. | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. | 0.727 |