Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TTYH2Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (505 aa)    
Predicted Functional Partners:
LRRC8E
Leucine rich repeat containing 8 VRAC subunit E.
      
 0.731
LRRC8C
Leucine rich repeat containing 8 VRAC subunit C.
      
 0.702
EVC2
EvC ciliary complex subunit 2.
     
 0.702
EFCAB7
EF-hand calcium binding domain 7.
     
  0.700
EVC
Uncharacterized protein.
     
  0.700
KCP
Kielin cysteine rich BMP regulator.
      
 0.669
TMEM243
Transmembrane protein 243.
      
 0.643
LRRC8A
Leucine rich repeat containing 8 VRAC subunit A.
   
  
 0.625
SLC35F6
Solute carrier family 35 member F6; May play a role as a nucleotide-sugar transporter.
      
 0.604
ENSOCUP00000024205
annotation not available
      
 0.577
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (22%) [HD]