Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FREM2FRAS1 related extracellular matrix 2. (2846 aa)    
Predicted Functional Partners:
FRAS1
Fraser extracellular matrix complex subunit 1.
   
0.913
FREM1
FRAS1 related extracellular matrix 1.
   
0.909
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
   
 0.909
NPNT
Nephronectin.
     
 0.895
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
    
  0.853
ITGA2B
Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.
   
  0.714
ITGB7
Integrin beta; Belongs to the integrin beta chain family.
    
  0.656
ITGB2
Integrin beta.
    
  0.656
GRIP1
Glutamate receptor interacting protein 1.
    
 0.626
ITGA5
Integrin subunit alpha 5; Belongs to the integrin alpha chain family.
   
 0.605
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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