Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)    
Predicted Functional Partners:
LEF1
Lymphoid enhancer binding factor 1.
    
 0.973
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    
 0.936
TCF7L1
Transcription factor 7 like 1.
    
 0.900
TCF7
Transcription factor 7.
    
 0.900
TCF7L2
Transcription factor 7 like 2.
    
 0.900
FOXO1
Fork-head domain-containing protein.
    
 0.821
CTNNB1
Catenin beta 1.
    
 0.812
FOXO3
Fork-head domain-containing protein.
    
 0.796
FOXO4
Forkhead box O4.
    
 0.790
MAP3K20
Mitogen-activated protein kinase kinase kinase 20.
    
 0.778
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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