ATMIN protein (Oryctolagus cuniculus) - STRING interaction network

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ATMIN

ATM interactor. (661 aa)

Predicted Functional Partners:

UBR5

0.839

ATM

0.773

DYNLL1

0.729

ENSOCUP00000040159

0.549

DYNLL2

0.544

ENSOCUP00000042214

0.544

WRNIP1

0.530

CHEK2

0.464

RAD18

0.464

TP53RK

0.448

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATM	ATMIN	ENSOCUP00000012638	ENSOCUP00000006744	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	ATM interactor.	0.773
ATM	CHEK2	ENSOCUP00000012638	ENSOCUP00000015499	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Checkpoint kinase 2.	0.998
ATM	RAD18	ENSOCUP00000012638	ENSOCUP00000029275	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Uncharacterized protein.	0.648
ATMIN	ATM	ENSOCUP00000006744	ENSOCUP00000012638	ATM interactor.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.773
ATMIN	CHEK2	ENSOCUP00000006744	ENSOCUP00000015499	ATM interactor.	Checkpoint kinase 2.	0.464
ATMIN	DYNLL1	ENSOCUP00000006744	ENSOCUP00000024256	ATM interactor.	Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.	0.729
ATMIN	DYNLL2	ENSOCUP00000006744	ENSOCUP00000014237	ATM interactor.	Dynein light chain.	0.544
ATMIN	ENSOCUP00000040159	ENSOCUP00000006744	ENSOCUP00000040159	ATM interactor.	Dynein light chain.	0.549
ATMIN	ENSOCUP00000042214	ENSOCUP00000006744	ENSOCUP00000042214	ATM interactor.	Dynein light chain.	0.544
ATMIN	RAD18	ENSOCUP00000006744	ENSOCUP00000029275	ATM interactor.	Uncharacterized protein.	0.464
ATMIN	TP53RK	ENSOCUP00000006744	ENSOCUP00000028821	ATM interactor.	TP53 regulating kinase.	0.448
ATMIN	UBR5	ENSOCUP00000006744	ENSOCUP00000007408	ATM interactor.	Ubiquitin protein ligase E3 component n-recognin 5.	0.839
ATMIN	WRNIP1	ENSOCUP00000006744	ENSOCUP00000004401	ATM interactor.	WRN helicase interacting protein 1.	0.530
CHEK2	ATM	ENSOCUP00000015499	ENSOCUP00000012638	Checkpoint kinase 2.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.998
CHEK2	ATMIN	ENSOCUP00000015499	ENSOCUP00000006744	Checkpoint kinase 2.	ATM interactor.	0.464
CHEK2	RAD18	ENSOCUP00000015499	ENSOCUP00000029275	Checkpoint kinase 2.	Uncharacterized protein.	0.613
DYNLL1	ATMIN	ENSOCUP00000024256	ENSOCUP00000006744	Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.	ATM interactor.	0.729
DYNLL1	DYNLL2	ENSOCUP00000024256	ENSOCUP00000014237	Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.	Dynein light chain.	0.995
DYNLL1	ENSOCUP00000040159	ENSOCUP00000024256	ENSOCUP00000040159	Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.	Dynein light chain.	0.546
DYNLL1	ENSOCUP00000042214	ENSOCUP00000024256	ENSOCUP00000042214	Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.	Dynein light chain.	0.554