Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ERAP1Endoplasmic reticulum aminopeptidase 1. (1034 aa)    
Predicted Functional Partners:
TAPBP
TAP binding protein.
   
 
 0.738
TPP2
Tripeptidyl peptidase 2.
   
 
 0.737
PSME1
Proteasome activator subunit 1.
   
  
 0.702
TNKS2
Poly [ADP-ribose] polymerase.
   
 
 0.685
B2M
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
   
 
 0.683
PSMB8
Proteasome subunit beta.
   
 
 0.662
PSME2
Proteasome activator subunit 2.
   
  
 0.652
PSMB10
Proteasome subunit beta.
   
 
 0.650
PSMB9
Uncharacterized protein.
   
  
 0.607
IL23R
Interleukin 23 receptor.
      
 0.579
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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