STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLBD2Phospholipase B-like; Putative phospholipase. (506 aa)    
Predicted Functional Partners:
PLB1
Phospholipase B1, membrane-associated; Membrane-associated phospholipase. Exhibits a calcium- independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Can convert phosphatidylcholine to fatty acids and glycerophosphocholine. Could be involved in uptake of dietary lipids, possibly including long chain retinyl esters. Belongs to the 'GDSL' lipolytic enzyme family. Phospholipase B1 subfamily.
   
  
 0.652
GAA
P-type domain-containing protein.
   
 
 0.640
SIAE
Sialic acid acetylesterase.
      
 0.615
RNASET2
Uncharacterized protein; Belongs to the RNase T2 family.
      
 0.596
GGH
Folate gamma-glutamyl hydrolase.
   
  
 0.576
PLA2G4A
Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response (By similarity).
     
 0.567
GLG1
Golgi glycoprotein 1.
      
 0.545
APLP2
Amyloid beta precursor like protein 2.
   
  
 0.545
PRCP
Prolylcarboxypeptidase.
   
  
 0.534
TPP1
Tripeptidyl peptidase 1.
   
  
 0.506
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: medium (64%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.