Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PUS10Pseudouridine synthase 10. (510 aa)    
Predicted Functional Partners:
PUS7
Pseudouridine synthase 7.
   
  
 0.853
PUS1
Pseudouridine synthase 1.
   
  
 0.839
PUS7L
Pseudouridine synthase 7 like.
   
  
 0.824
TRMT5
tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.
   
  
 0.810
TRUB2
Uncharacterized protein.
   
  
 0.809
PUS3
Pseudouridine synthase 3.
   
  
 0.801
ABITRAM
Actin binding transcription modulator.
    
   0.774
RPUSD4
RNA pseudouridine synthase D4.
      
 0.771
RPUSD2
RNA pseudouridine synthase domain containing 2.
      
 0.761
TRMT12
tRNA methyltransferase 12 homolog.
   
  
 0.738
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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