STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NISCHNischarin. (1484 aa)    
Predicted Functional Partners:
ITGA5
Integrin subunit alpha 5; Belongs to the integrin alpha chain family.
      
 0.699
LIMK1
LIM domain kinase 1.
     
 0.674
RAB21
RAB21, member RAS oncogene family.
      
 0.672
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
     
 0.600
RND2
Rho family GTPase 2.
   
  0.531
RAB42
RAB42, member RAS oncogene family.
   
 0.528
PIP5KL1
Phosphatidylinositol-4-phosphate 5-kinase like 1.
   
  
 0.528
RND3
Rho family GTPase 3.
   
  0.522
EPOR
Erythropoietin receptor.
   
  
 0.518
FLNB
Filamin-B; Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton (By similarity).
   
  
 0.501
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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