ETV4 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ETV4

ETS variant 4. (481 aa)

Predicted Functional Partners:

NCOA3

0.758

TMPRSS2

0.685

SPRY4

0.678

DUSP6

0.657

SPRY2

0.650

COP1

0.634

NCOA1

0.603

WNT7A

0.587

SLC45A3

0.582

DUSP4

0.572

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COP1	ETV4	ENSOCUP00000004743	ENSOCUP00000006941	COP1 E3 ubiquitin ligase.	ETS variant 4.	0.634
DUSP4	ETV4	ENSOCUP00000003222	ENSOCUP00000006941	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	ETS variant 4.	0.572
DUSP4	SPRY2	ENSOCUP00000003222	ENSOCUP00000008277	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Sprouty RTK signaling antagonist 2.	0.657
DUSP4	SPRY4	ENSOCUP00000003222	ENSOCUP00000018562	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Sprouty RTK signaling antagonist 4.	0.670
DUSP6	ETV4	ENSOCUP00000002520	ENSOCUP00000006941	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	ETS variant 4.	0.657
DUSP6	SPRY2	ENSOCUP00000002520	ENSOCUP00000008277	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Sprouty RTK signaling antagonist 2.	0.742
DUSP6	SPRY4	ENSOCUP00000002520	ENSOCUP00000018562	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Sprouty RTK signaling antagonist 4.	0.759
ETV4	COP1	ENSOCUP00000006941	ENSOCUP00000004743	ETS variant 4.	COP1 E3 ubiquitin ligase.	0.634
ETV4	DUSP4	ENSOCUP00000006941	ENSOCUP00000003222	ETS variant 4.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.572
ETV4	DUSP6	ENSOCUP00000006941	ENSOCUP00000002520	ETS variant 4.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.657
ETV4	NCOA1	ENSOCUP00000006941	ENSOCUP00000013252	ETS variant 4.	Nuclear receptor coactivator.	0.603
ETV4	NCOA3	ENSOCUP00000006941	ENSOCUP00000037443	ETS variant 4.	Nuclear receptor coactivator.	0.758
ETV4	SLC45A3	ENSOCUP00000006941	ENSOCUP00000017971	ETS variant 4.	Solute carrier family 45 member 3.	0.582
ETV4	SPRY2	ENSOCUP00000006941	ENSOCUP00000008277	ETS variant 4.	Sprouty RTK signaling antagonist 2.	0.650
ETV4	SPRY4	ENSOCUP00000006941	ENSOCUP00000018562	ETS variant 4.	Sprouty RTK signaling antagonist 4.	0.678
ETV4	TMPRSS2	ENSOCUP00000006941	ENSOCUP00000018355	ETS variant 4.	Transmembrane serine protease 2; Belongs to the peptidase S1 family.	0.685
ETV4	WNT7A	ENSOCUP00000006941	ENSOCUP00000026823	ETS variant 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.587
NCOA1	ETV4	ENSOCUP00000013252	ENSOCUP00000006941	Nuclear receptor coactivator.	ETS variant 4.	0.603
NCOA1	NCOA3	ENSOCUP00000013252	ENSOCUP00000037443	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.983
NCOA3	ETV4	ENSOCUP00000037443	ENSOCUP00000006941	Nuclear receptor coactivator.	ETS variant 4.	0.758