DCAF12 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

DCAF12

DDB1 and CUL4 associated factor 12. (453 aa)

Predicted Functional Partners:

DDB1

0.984

DCAF4

0.942

DCAF6

0.926

DCAF5

0.916

DCAF11

0.889

STRADB

0.858

TRPC4AP

0.827

CUL4A

0.824

CCT5

0.800

DCAF10

0.790

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCT5	DCAF12	ENSOCUP00000018287	ENSOCUP00000006949	Chaperonin containing TCP1 subunit 5.	DDB1 and CUL4 associated factor 12.	0.800
CCT5	DCAF5	ENSOCUP00000018287	ENSOCUP00000008866	Chaperonin containing TCP1 subunit 5.	DDB1 and CUL4 associated factor 5.	0.753
CCT5	DDB1	ENSOCUP00000018287	ENSOCUP00000001429	Chaperonin containing TCP1 subunit 5.	Damage specific DNA binding protein 1.	0.689
CUL4A	DCAF10	ENSOCUP00000008283	ENSOCUP00000002108	Cullin 4A; Belongs to the cullin family.	DDB1 and CUL4 associated factor 10.	0.926
CUL4A	DCAF11	ENSOCUP00000008283	ENSOCUP00000030356	Cullin 4A; Belongs to the cullin family.	DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.	0.992
CUL4A	DCAF12	ENSOCUP00000008283	ENSOCUP00000006949	Cullin 4A; Belongs to the cullin family.	DDB1 and CUL4 associated factor 12.	0.824
CUL4A	DCAF4	ENSOCUP00000008283	ENSOCUP00000029290	Cullin 4A; Belongs to the cullin family.	WD_REPEATS_REGION domain-containing protein.	0.949
CUL4A	DCAF5	ENSOCUP00000008283	ENSOCUP00000008866	Cullin 4A; Belongs to the cullin family.	DDB1 and CUL4 associated factor 5.	0.955
CUL4A	DCAF6	ENSOCUP00000008283	ENSOCUP00000031538	Cullin 4A; Belongs to the cullin family.	Uncharacterized protein.	0.930
CUL4A	DDB1	ENSOCUP00000008283	ENSOCUP00000001429	Cullin 4A; Belongs to the cullin family.	Damage specific DNA binding protein 1.	0.999
CUL4A	TRPC4AP	ENSOCUP00000008283	ENSOCUP00000039070	Cullin 4A; Belongs to the cullin family.	Transient receptor potential cation channel subfamily C member 4 associated protein.	0.895
DCAF10	CUL4A	ENSOCUP00000002108	ENSOCUP00000008283	DDB1 and CUL4 associated factor 10.	Cullin 4A; Belongs to the cullin family.	0.926
DCAF10	DCAF11	ENSOCUP00000002108	ENSOCUP00000030356	DDB1 and CUL4 associated factor 10.	DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.	0.857
DCAF10	DCAF12	ENSOCUP00000002108	ENSOCUP00000006949	DDB1 and CUL4 associated factor 10.	DDB1 and CUL4 associated factor 12.	0.790
DCAF10	DCAF4	ENSOCUP00000002108	ENSOCUP00000029290	DDB1 and CUL4 associated factor 10.	WD_REPEATS_REGION domain-containing protein.	0.932
DCAF10	DCAF5	ENSOCUP00000002108	ENSOCUP00000008866	DDB1 and CUL4 associated factor 10.	DDB1 and CUL4 associated factor 5.	0.970
DCAF10	DCAF6	ENSOCUP00000002108	ENSOCUP00000031538	DDB1 and CUL4 associated factor 10.	Uncharacterized protein.	0.854
DCAF10	DDB1	ENSOCUP00000002108	ENSOCUP00000001429	DDB1 and CUL4 associated factor 10.	Damage specific DNA binding protein 1.	0.964
DCAF10	TRPC4AP	ENSOCUP00000002108	ENSOCUP00000039070	DDB1 and CUL4 associated factor 10.	Transient receptor potential cation channel subfamily C member 4 associated protein.	0.547
DCAF11	CUL4A	ENSOCUP00000030356	ENSOCUP00000008283	DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.	Cullin 4A; Belongs to the cullin family.	0.992