G1SUF2_RABIT protein (Oryctolagus cuniculus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

G1SUF2_RABIT

Ig-like domain-containing protein. (94 aa)

Predicted Functional Partners:

G1SK63_RABIT

0.782

G1SF96_RABIT

0.605

LAC_RABIT

0.605

IGLL1

0.605

G1U8Q5_RABIT

0.502

APP

0.452

TFPI

0.450

TNFRSF17

0.440

NT5E

0.440

JCHAIN

0.430

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	G1SK63_RABIT	ENSOCUP00000009130	ENSOCUP00000003180	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Uncharacterized protein.	0.669
APP	G1SUF2_RABIT	ENSOCUP00000009130	ENSOCUP00000006982	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Ig-like domain-containing protein.	0.452
G1SF96_RABIT	G1SK63_RABIT	ENSOCUP00000001173	ENSOCUP00000003180	Ig-like domain-containing protein.	Uncharacterized protein.	0.881
G1SF96_RABIT	G1SUF2_RABIT	ENSOCUP00000001173	ENSOCUP00000006982	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.605
G1SF96_RABIT	JCHAIN	ENSOCUP00000001173	ENSOCUP00000023316	Ig-like domain-containing protein.	Immunoglobulin J chain; Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.	0.622
G1SF96_RABIT	NT5E	ENSOCUP00000001173	ENSOCUP00000026796	Ig-like domain-containing protein.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.583
G1SK63_RABIT	APP	ENSOCUP00000003180	ENSOCUP00000009130	Uncharacterized protein.	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.669
G1SK63_RABIT	G1SF96_RABIT	ENSOCUP00000003180	ENSOCUP00000001173	Uncharacterized protein.	Ig-like domain-containing protein.	0.881
G1SK63_RABIT	G1SUF2_RABIT	ENSOCUP00000003180	ENSOCUP00000006982	Uncharacterized protein.	Ig-like domain-containing protein.	0.782
G1SK63_RABIT	IGLL1	ENSOCUP00000003180	ENSOCUP00000015640	Uncharacterized protein.	Lambda5.	0.881
G1SK63_RABIT	JCHAIN	ENSOCUP00000003180	ENSOCUP00000023316	Uncharacterized protein.	Immunoglobulin J chain; Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.	0.509
G1SK63_RABIT	LAC_RABIT	ENSOCUP00000003180	ENSOCUP00000010579	Uncharacterized protein.	Ig lambda chain C region.	0.881
G1SK63_RABIT	TFPI	ENSOCUP00000003180	ENSOCUP00000007133	Uncharacterized protein.	Tissue factor pathway inhibitor; Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.	0.774
G1SUF2_RABIT	APP	ENSOCUP00000006982	ENSOCUP00000009130	Ig-like domain-containing protein.	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.452
G1SUF2_RABIT	G1SF96_RABIT	ENSOCUP00000006982	ENSOCUP00000001173	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.605
G1SUF2_RABIT	G1SK63_RABIT	ENSOCUP00000006982	ENSOCUP00000003180	Ig-like domain-containing protein.	Uncharacterized protein.	0.782
G1SUF2_RABIT	G1U8Q5_RABIT	ENSOCUP00000006982	ENSOCUP00000025822	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.502
G1SUF2_RABIT	IGLL1	ENSOCUP00000006982	ENSOCUP00000015640	Ig-like domain-containing protein.	Lambda5.	0.605
G1SUF2_RABIT	JCHAIN	ENSOCUP00000006982	ENSOCUP00000023316	Ig-like domain-containing protein.	Immunoglobulin J chain; Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.	0.430
G1SUF2_RABIT	LAC_RABIT	ENSOCUP00000006982	ENSOCUP00000010579	Ig-like domain-containing protein.	Ig lambda chain C region.	0.605