STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM59Transmembrane protein 59. (389 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
    
 0.978
STIP1
Stress induced phosphoprotein 1.
   
 0.819
DNAJC2
DnaJ heat shock protein family (Hsp40) member C2.
   
 0.779
BAG3
BCL2 associated athanogene 3.
   
 0.731
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.727
DNAJC10
DnaJ heat shock protein family (Hsp40) member C10.
  
 0.720
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
    
 0.719
ATG16L1
Autophagy related 16 like 1.
    
 
 0.698
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 0.659
HSP90AA1
Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]
   
 0.650
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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