PNLIPRP1 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

PNLIPRP1

Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (473 aa)

Predicted Functional Partners:

CLPS

0.980

MGLL

0.922

LIPF

0.915

LPL

0.915

LIPC

0.911

G1THC3_RABIT

0.905

PLPP4

0.903

ENSOCUP00000037325

0.903

PNLIPRP2

0.903

G1TAW2_RABIT

0.902

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLPS	ENSOCUP00000037325	ENSOCUP00000024363	ENSOCUP00000037325	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.976
CLPS	LIPC	ENSOCUP00000024363	ENSOCUP00000001411	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	Hepatic triacylglycerol lipase; Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin (By similarity).	0.492
CLPS	PNLIPRP1	ENSOCUP00000024363	ENSOCUP00000007072	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.980
CLPS	PNLIPRP2	ENSOCUP00000024363	ENSOCUP00000048398	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.980
ENSOCUP00000037325	CLPS	ENSOCUP00000037325	ENSOCUP00000024363	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	0.976
ENSOCUP00000037325	G1TAW2_RABIT	ENSOCUP00000037325	ENSOCUP00000013832	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Uncharacterized protein.	0.902
ENSOCUP00000037325	G1THC3_RABIT	ENSOCUP00000037325	ENSOCUP00000016329	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	PNPLA domain-containing protein.	0.905
ENSOCUP00000037325	LIPC	ENSOCUP00000037325	ENSOCUP00000001411	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Hepatic triacylglycerol lipase; Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin (By similarity).	0.940
ENSOCUP00000037325	LIPF	ENSOCUP00000037325	ENSOCUP00000010744	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.915
ENSOCUP00000037325	LPL	ENSOCUP00000037325	ENSOCUP00000027265	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.917
ENSOCUP00000037325	MGLL	ENSOCUP00000037325	ENSOCUP00000034747	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Uncharacterized protein.	0.913
ENSOCUP00000037325	PLPP4	ENSOCUP00000037325	ENSOCUP00000029716	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	acidPPc domain-containing protein.	0.903
ENSOCUP00000037325	PNLIPRP1	ENSOCUP00000037325	ENSOCUP00000007072	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.903
ENSOCUP00000037325	PNLIPRP2	ENSOCUP00000037325	ENSOCUP00000048398	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.903
G1TAW2_RABIT	ENSOCUP00000037325	ENSOCUP00000013832	ENSOCUP00000037325	Uncharacterized protein.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.902
G1TAW2_RABIT	G1THC3_RABIT	ENSOCUP00000013832	ENSOCUP00000016329	Uncharacterized protein.	PNPLA domain-containing protein.	0.914
G1TAW2_RABIT	LIPC	ENSOCUP00000013832	ENSOCUP00000001411	Uncharacterized protein.	Hepatic triacylglycerol lipase; Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin (By similarity).	0.900
G1TAW2_RABIT	LIPF	ENSOCUP00000013832	ENSOCUP00000010744	Uncharacterized protein.	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.906
G1TAW2_RABIT	LPL	ENSOCUP00000013832	ENSOCUP00000027265	Uncharacterized protein.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.912
G1TAW2_RABIT	MGLL	ENSOCUP00000013832	ENSOCUP00000034747	Uncharacterized protein.	Uncharacterized protein.	0.915