STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100354435Uncharacterized protein; Belongs to the heat shock protein 70 family. (611 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
    
 0.978
STIP1
Stress induced phosphoprotein 1.
   
 0.830
DNAJC2
DnaJ heat shock protein family (Hsp40) member C2.
   
 0.779
DNAJB9
DnaJ heat shock protein family (Hsp40) member B9.
  
 0.767
DNAJA2
DnaJ heat shock protein family (Hsp40) member A2.
  
 0.765
ENSOCUP00000038964
J domain-containing protein.
  
 0.755
DNAJB4
DnaJ heat shock protein family (Hsp40) member B4.
  
 0.753
DNAJB5
DnaJ heat shock protein family (Hsp40) member B5.
  
 0.740
NR3C1
Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...]
    
 0.740
BAG3
BCL2 associated athanogene 3.
   
 0.739
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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