UBA1 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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co-expression

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gene neighborhood

gene co-occurrence

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Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC34	ISG15	ENSOCUP00000019232	ENSOCUP00000029108	Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family.	ISG15 ubiquitin like modifier.	0.418
CDC34	UBA1	ENSOCUP00000019232	ENSOCUP00000007237	Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-like modifier-activating enzyme 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (By similarity).	0.985
CDC34	UBE2D2	ENSOCUP00000019232	ENSOCUP00000026812	Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.430
CDC34	UBE2G2	ENSOCUP00000019232	ENSOCUP00000033895	Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family.	0.445
CDC34	UBE2H	ENSOCUP00000019232	ENSOCUP00000042107	Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family.	0.576
CDC34	UBE2K	ENSOCUP00000019232	ENSOCUP00000005089	Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.	0.483
CDC34	UBE2R2	ENSOCUP00000019232	ENSOCUP00000024929	Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2 R2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. May be involved in degradation of katenin; Belongs to the ubiquitin-conjugating enzyme family.	0.904
CDC34	UBE2S	ENSOCUP00000019232	ENSOCUP00000011191	Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family.	0.463
ISG15	CDC34	ENSOCUP00000029108	ENSOCUP00000019232	ISG15 ubiquitin like modifier.	Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family.	0.418
ISG15	LOC100354960	ENSOCUP00000029108	ENSOCUP00000027269	ISG15 ubiquitin like modifier.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.656
ISG15	UBA1	ENSOCUP00000029108	ENSOCUP00000007237	ISG15 ubiquitin like modifier.	Ubiquitin-like modifier-activating enzyme 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (By similarity).	0.968
ISG15	UBE2G2	ENSOCUP00000029108	ENSOCUP00000033895	ISG15 ubiquitin like modifier.	Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family.	0.478
ISG15	UBE2H	ENSOCUP00000029108	ENSOCUP00000042107	ISG15 ubiquitin like modifier.	Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family.	0.531
ISG15	UBE2K	ENSOCUP00000029108	ENSOCUP00000005089	ISG15 ubiquitin like modifier.	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.	0.583
ISG15	UBE2R2	ENSOCUP00000029108	ENSOCUP00000024929	ISG15 ubiquitin like modifier.	Ubiquitin-conjugating enzyme E2 R2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. May be involved in degradation of katenin; Belongs to the ubiquitin-conjugating enzyme family.	0.418
ISG15	UBE2S	ENSOCUP00000029108	ENSOCUP00000011191	ISG15 ubiquitin like modifier.	Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family.	0.453
LOC100354960	ISG15	ENSOCUP00000027269	ENSOCUP00000029108	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	ISG15 ubiquitin like modifier.	0.656
LOC100354960	UBA1	ENSOCUP00000027269	ENSOCUP00000007237	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-like modifier-activating enzyme 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (By similarity).	0.976
LOC100354960	UBE2D1	ENSOCUP00000027269	ENSOCUP00000032198	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.517
LOC100354960	UBE2D2	ENSOCUP00000027269	ENSOCUP00000026812	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.441