Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OSBPL1AOxysterol-binding protein; Belongs to the OSBP family. (950 aa)    
Predicted Functional Partners:
RAB7A
Ras-related protein Rab-7a; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth- factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism (By simi [...]
    
 0.883
ENSOCUP00000049020
MSP domain-containing protein.
    
 
 0.862
VAPB
VAMP associated protein B and C.
    
 
 0.855
ENSOCUP00000046169
Uncharacterized protein.
    
 0.833
MOSPD2
Motile sperm domain containing 2.
    
 
 0.811
RILP
Rab interacting lysosomal protein.
    
 0.809
RAB31
MSP domain-containing protein.
    
 
 0.773
ZNF621
Zinc finger protein 621.
      
 0.640
ZFAND6
Zinc finger AN1-type containing 6.
   
  
 0.601
RILPL1
Rab interacting lysosomal protein like 1.
    
 0.582
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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