CDC25C protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CDC25C

Cell division cycle 25C. (483 aa)

Predicted Functional Partners:

CDK1

0.990

PLK1

0.985

CDK2

0.976

CHEK2

0.970

CCNB2

0.956

CCNB1

0.955

CCNE2

0.945

CDK4

0.938

WEE1

0.935

YWHAB

0.929

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNB1	CCNB2	ENSOCUP00000003748	ENSOCUP00000001415	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin B2; Belongs to the cyclin family.	0.449
CCNB1	CCNE2	ENSOCUP00000003748	ENSOCUP00000004682	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin E2; Belongs to the cyclin family.	0.810
CCNB1	CDC25C	ENSOCUP00000003748	ENSOCUP00000007258	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cell division cycle 25C.	0.955
CCNB1	CDK1	ENSOCUP00000003748	ENSOCUP00000002479	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.	0.999
CCNB1	CDK2	ENSOCUP00000003748	ENSOCUP00000034758	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	0.981
CCNB1	CDK4	ENSOCUP00000003748	ENSOCUP00000010738	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.	0.941
CCNB1	CHEK2	ENSOCUP00000003748	ENSOCUP00000015499	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Checkpoint kinase 2.	0.633
CCNB1	PLK1	ENSOCUP00000003748	ENSOCUP00000007325	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Serine/threonine-protein kinase PLK.	0.996
CCNB1	WEE1	ENSOCUP00000003748	ENSOCUP00000011255	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Wee1-like protein kinase.	0.860
CCNB1	YWHAB	ENSOCUP00000003748	ENSOCUP00000034985	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.	0.499
CCNB2	CCNB1	ENSOCUP00000001415	ENSOCUP00000003748	Cyclin B2; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.449
CCNB2	CCNE2	ENSOCUP00000001415	ENSOCUP00000004682	Cyclin B2; Belongs to the cyclin family.	Cyclin E2; Belongs to the cyclin family.	0.821
CCNB2	CDC25C	ENSOCUP00000001415	ENSOCUP00000007258	Cyclin B2; Belongs to the cyclin family.	Cell division cycle 25C.	0.956
CCNB2	CDK1	ENSOCUP00000001415	ENSOCUP00000002479	Cyclin B2; Belongs to the cyclin family.	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.	0.999
CCNB2	CDK2	ENSOCUP00000001415	ENSOCUP00000034758	Cyclin B2; Belongs to the cyclin family.	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	0.979
CCNB2	CDK4	ENSOCUP00000001415	ENSOCUP00000010738	Cyclin B2; Belongs to the cyclin family.	Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.	0.932
CCNB2	CHEK2	ENSOCUP00000001415	ENSOCUP00000015499	Cyclin B2; Belongs to the cyclin family.	Checkpoint kinase 2.	0.566
CCNB2	PLK1	ENSOCUP00000001415	ENSOCUP00000007325	Cyclin B2; Belongs to the cyclin family.	Serine/threonine-protein kinase PLK.	0.996
CCNB2	WEE1	ENSOCUP00000001415	ENSOCUP00000011255	Cyclin B2; Belongs to the cyclin family.	Wee1-like protein kinase.	0.880
CCNB2	YWHAB	ENSOCUP00000001415	ENSOCUP00000034985	Cyclin B2; Belongs to the cyclin family.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.	0.499