| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CUL1 | FBXO4 | ENSOCUP00000002198 | ENSOCUP00000007984 | Cullin 1; Belongs to the cullin family. | F-box protein 4. | 0.979 |
| CUL1 | FBXW7 | ENSOCUP00000002198 | ENSOCUP00000007292 | Cullin 1; Belongs to the cullin family. | F-box and WD repeat domain containing 7. | 0.991 |
| CUL1 | JUN | ENSOCUP00000002198 | ENSOCUP00000040325 | Cullin 1; Belongs to the cullin family. | BZIP domain-containing protein; Belongs to the bZIP family. | 0.574 |
| CUL1 | MCL1 | ENSOCUP00000002198 | ENSOCUP00000010452 | Cullin 1; Belongs to the cullin family. | MCL1 apoptosis regulator, BCL2 family member. | 0.790 |
| CUL1 | MYC | ENSOCUP00000002198 | ENSOCUP00000012281 | Cullin 1; Belongs to the cullin family. | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. | 0.855 |
| CUL1 | NFKB2 | ENSOCUP00000002198 | ENSOCUP00000004978 | Cullin 1; Belongs to the cullin family. | Nuclear factor kappa B subunit 2. | 0.558 |
| CUL1 | SKP1 | ENSOCUP00000002198 | ENSOCUP00000020468 | Cullin 1; Belongs to the cullin family. | Uncharacterized protein; Belongs to the SKP1 family. | 0.997 |
| FBXO4 | CUL1 | ENSOCUP00000007984 | ENSOCUP00000002198 | F-box protein 4. | Cullin 1; Belongs to the cullin family. | 0.979 |
| FBXO4 | FBXW7 | ENSOCUP00000007984 | ENSOCUP00000007292 | F-box protein 4. | F-box and WD repeat domain containing 7. | 0.917 |
| FBXO4 | SKP1 | ENSOCUP00000007984 | ENSOCUP00000020468 | F-box protein 4. | Uncharacterized protein; Belongs to the SKP1 family. | 0.864 |
| FBXW7 | CUL1 | ENSOCUP00000007292 | ENSOCUP00000002198 | F-box and WD repeat domain containing 7. | Cullin 1; Belongs to the cullin family. | 0.991 |
| FBXW7 | FBXO4 | ENSOCUP00000007292 | ENSOCUP00000007984 | F-box and WD repeat domain containing 7. | F-box protein 4. | 0.917 |
| FBXW7 | JUN | ENSOCUP00000007292 | ENSOCUP00000040325 | F-box and WD repeat domain containing 7. | BZIP domain-containing protein; Belongs to the bZIP family. | 0.969 |
| FBXW7 | KLF5 | ENSOCUP00000007292 | ENSOCUP00000010102 | F-box and WD repeat domain containing 7. | Uncharacterized protein. | 0.948 |
| FBXW7 | MCL1 | ENSOCUP00000007292 | ENSOCUP00000010452 | F-box and WD repeat domain containing 7. | MCL1 apoptosis regulator, BCL2 family member. | 0.967 |
| FBXW7 | MTOR | ENSOCUP00000007292 | ENSOCUP00000011253 | F-box and WD repeat domain containing 7. | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. | 0.964 |
| FBXW7 | MYC | ENSOCUP00000007292 | ENSOCUP00000012281 | F-box and WD repeat domain containing 7. | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. | 0.978 |
| FBXW7 | NFKB2 | ENSOCUP00000007292 | ENSOCUP00000004978 | F-box and WD repeat domain containing 7. | Nuclear factor kappa B subunit 2. | 0.923 |
| FBXW7 | SKP1 | ENSOCUP00000007292 | ENSOCUP00000020468 | F-box and WD repeat domain containing 7. | Uncharacterized protein; Belongs to the SKP1 family. | 0.936 |
| FBXW7 | TP53 | ENSOCUP00000007292 | ENSOCUP00000000989 | F-box and WD repeat domain containing 7. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.930 |
