Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PLK1Serine/threonine-protein kinase PLK. (604 aa)    
Predicted Functional Partners:
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.999
CDC20B
Cell division cycle 20B.
   
 0.999
BUB1B
Uncharacterized protein.
   
 0.999
FOXM1
Forkhead box M1.
   
 0.998
BORA
BORA aurora kinase A activator.
   
 0.998
CCNB2
Cyclin B2; Belongs to the cyclin family.
   
 0.996
CCNB1
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.996
KIF2C
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.996
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.996
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
0.995
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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