Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EEF1A1Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. (462 aa)    
Predicted Functional Partners:
EEF1G
Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.
   
 0.978
RPS5
Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.
  
 0.956
ENSOCUP00000027896
Uncharacterized protein; Belongs to the GST superfamily.
   
 0.953
RPL4
Ribos_L4_asso_C domain-containing protein.
   
 0.949
RPS15
Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
   
 0.944
RPLP0
60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
   
 0.943
RPS3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
   
 0.943
EEF1B
Elongation factor 1-beta; EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.
   
 0.943
RPS6
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
   
 0.929
RPS25
40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.
   
 0.927
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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