STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNNTenascin N. (1298 aa)    
Predicted Functional Partners:
DENR
Density-regulated protein; Belongs to the DENR family.
      
 0.742
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
    
   0.694
TNR
Tenascin R.
   
 
0.687
TNC
Tenascin C.
     
0.686
SVEP1
Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1.
    
0.681
ACAN
Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.
   
 0.642
SDC3
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
   
 
  0.631
BCAN
Brevican.
   
 0.622
FAM20A
FAM20A golgi associated secretory pathway pseudokinase.
   
 
  0.518
FAM20B
FAM20B glycosaminoglycan xylosylkinase.
   
 
  0.518
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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