STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHM1Pleckstrin homology and RUN domain containing M1. (1156 aa)    
Predicted Functional Partners:
SNAP29
t-SNARE coiled-coil homology domain-containing protein.
      
 0.863
VPS39
VPS39 subunit of HOPS complex.
   
 
 0.856
OSTM1
Uncharacterized protein.
   
  
 0.808
STX17
Syntaxin 17; Belongs to the syntaxin family.
      
 0.799
VPS11
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
    
 
 0.774
MAP1LC3C
Uncharacterized protein.
    
 
 0.768
ARL8B
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.759
VAMP8
Vesicle associated membrane protein 8.
   
  
 0.735
EPG5
Ectopic P-granules autophagy protein 5 homolog.
   
  
 0.720
GABARAP
Gamma-aminobutyric acid receptor-associated protein; Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity); Belongs to the ATG8 family.
    
 
 0.716
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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