PRUNE2 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PRUNE2

Prune homolog 2 with BCH domain. (3071 aa)

Predicted Functional Partners:

ENSOCUP00000041459

0.818

ZSCAN23

0.568

SDHA

0.542

SLC15A5

0.540

CARNMT1

0.530

PLEKHA6

0.527

OBSCN

0.498

ADAR

0.485

DDIT4L

0.480

TMEM217

0.465

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAR	PRUNE2	ENSOCUP00000048374	ENSOCUP00000007398	Adenosine deaminase RNA specific.	Prune homolog 2 with BCH domain.	0.485
CARNMT1	PRUNE2	ENSOCUP00000014622	ENSOCUP00000007398	Carnosine N-methyltransferase 1.	Prune homolog 2 with BCH domain.	0.530
DDIT4L	PRUNE2	ENSOCUP00000013971	ENSOCUP00000007398	DNA damage inducible transcript 4 like.	Prune homolog 2 with BCH domain.	0.480
ENSOCUP00000041459	PRUNE2	ENSOCUP00000041459	ENSOCUP00000007398	Uncharacterized protein.	Prune homolog 2 with BCH domain.	0.818
OBSCN	PRUNE2	ENSOCUP00000009937	ENSOCUP00000007398	Uncharacterized protein.	Prune homolog 2 with BCH domain.	0.498
PLEKHA6	PRUNE2	ENSOCUP00000017767	ENSOCUP00000007398	Pleckstrin homology domain containing A6.	Prune homolog 2 with BCH domain.	0.527
PRUNE2	ADAR	ENSOCUP00000007398	ENSOCUP00000048374	Prune homolog 2 with BCH domain.	Adenosine deaminase RNA specific.	0.485
PRUNE2	CARNMT1	ENSOCUP00000007398	ENSOCUP00000014622	Prune homolog 2 with BCH domain.	Carnosine N-methyltransferase 1.	0.530
PRUNE2	DDIT4L	ENSOCUP00000007398	ENSOCUP00000013971	Prune homolog 2 with BCH domain.	DNA damage inducible transcript 4 like.	0.480
PRUNE2	ENSOCUP00000041459	ENSOCUP00000007398	ENSOCUP00000041459	Prune homolog 2 with BCH domain.	Uncharacterized protein.	0.818
PRUNE2	OBSCN	ENSOCUP00000007398	ENSOCUP00000009937	Prune homolog 2 with BCH domain.	Uncharacterized protein.	0.498
PRUNE2	PLEKHA6	ENSOCUP00000007398	ENSOCUP00000017767	Prune homolog 2 with BCH domain.	Pleckstrin homology domain containing A6.	0.527
PRUNE2	SDHA	ENSOCUP00000007398	ENSOCUP00000025370	Prune homolog 2 with BCH domain.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.542
PRUNE2	SLC15A5	ENSOCUP00000007398	ENSOCUP00000011610	Prune homolog 2 with BCH domain.	Solute carrier family 15 member 5.	0.540
PRUNE2	TMEM217	ENSOCUP00000007398	ENSOCUP00000021187	Prune homolog 2 with BCH domain.	Uncharacterized protein.	0.465
PRUNE2	ZSCAN23	ENSOCUP00000007398	ENSOCUP00000026529	Prune homolog 2 with BCH domain.	Zinc finger and SCAN domain containing 23.	0.568
SDHA	PRUNE2	ENSOCUP00000025370	ENSOCUP00000007398	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	Prune homolog 2 with BCH domain.	0.542
SLC15A5	PRUNE2	ENSOCUP00000011610	ENSOCUP00000007398	Solute carrier family 15 member 5.	Prune homolog 2 with BCH domain.	0.540
TMEM217	PRUNE2	ENSOCUP00000021187	ENSOCUP00000007398	Uncharacterized protein.	Prune homolog 2 with BCH domain.	0.465
ZSCAN23	PRUNE2	ENSOCUP00000026529	ENSOCUP00000007398	Zinc finger and SCAN domain containing 23.	Prune homolog 2 with BCH domain.	0.568