STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2769 aa)    
Predicted Functional Partners:
TRIP12
Thyroid hormone receptor interactor 12.
   
  
0.987
UBR2
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
  
 0.841
UBR1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
  
 0.827
DDB1
Damage specific DNA binding protein 1.
    
 
 0.797
ENSOCUP00000044498
Ribosomal_L40e domain-containing protein.
    
   0.772
UBR4
Ubiquitin protein ligase E3 component n-recognin 4.
   
  
0.735
ATMIN
ATM interactor.
   
 
 0.734
DCAF1
DDB1 and CUL4 associated factor 1.
   
 
 0.716
PAIP1
MIF4G domain-containing protein.
   
 
 0.713
U3KMZ1_RABIT
MIF4G domain-containing protein.
   
 
 0.709
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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